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EFFICIENCY GAINS IN LITERATURE REVIEW

The ROI of MadeAi™ for Literature Reviews

Traditional literature reviews in life sciences are slow, resource-intensive, and expensive. On average, in-house teams spend over 1,000 hours and $90,000 to complete a single review.

MadeAi™ changes that. By combining GenAI automation with expert services, MadeAi reduces both cost and effort—while maintaining the rigor, transparency, and quality demanded by regulatory and HTA stakeholders.

ROI at a Glance

The detailed model below demonstrates how proven GenAI capabilities are leveraged to accelerate certain phases of the literature review process. To understand how this model plays out in day-to-day research checkout our whitepaper on The ROI of GenAI Enablement for the Literature Review Process that details the considerations for the model and compares various delivery methods for conducting a literature review.

An average project size of 2,500 initial article hits was considered for this analysis of time savings.
Phase for Literature Review Process Traditional Human Approach (hours) Madeai-LR AI (hours) Madeai-LR
Human Validation (hours)
Total (hours) Savings (%) Time Saving Areas
Search 2 - 0.08 0.08 96% Integration to PubMed & Embase
Deduplication 2 0.008 - 0.008 100%
  • Isolates 100% duplicates
  • Groups similar articles for quick review (90-99.9%)
Title & Abstract Screening (Custom - 2,500 articles) 400 0.2 80 80.20 80%
  • AI tagwise decisions backed with sentence highlight and overall reasons
  • Collaborator logics
  • Isolation of conflicted articles
  • Filter a pattern of articles (Sort & filter)
Full Text Screening (Custom - 500 articles) 320 0.5 200 200.50 37%
  • All benefits as in T&A screening
  • Full-text purchase via CCC RightFind
Full-text Purchase and Management 10 - 5 5.00 50% Access to CCC RightFind
Data Extraction (Summary-Level Extraction - 25 articles) 20 0.25 10 10.25 49% Links to source text enhance validation
Quality Appraisal
(25 articles)
40 - 35 35 13% Converts results to charts and tables based on standard appraisal tools
Individual Article Summary (SAS - 25 articles) 120 0.5 50 50.5 58%
  • AI summarizer with quick backtracking
  • Sentence highlighter
Literature Summary
(1 MAS)
25 0.17 10 10.17 59%
  • AI summarizer with quick backtracking
  • Sentence highlighter
  • Referencing citations
CO Report (Literature Review section) 80 0.2 50 50.2 37%
  • AI summarizer with quick backtracking
  • Sentence highlighter
  • Referencing citations
PRISMA Chart 4 Real time 0 0 100% Automatically populated chart in no time
Total 1,073 1.828 490.08 441.9 54%

Why it Matters

  • Cut Time & Cost: Reduce review expenses by more than half while accelerating project delivery.
  • Scale Confidently: Handle large review volumes without overburdening internal teams.
  • Maintain Rigor: Built-in transparency and validated AI processes ensure scientific quality.
  • Leverage Expertise: Access a seasoned services team with experience co-authoring peer-reviewed publications.
  • Bottom Line: MadeAi transforms literature reviews from a resource-heavy bottleneck into a faster, more cost-effective, and strategically valuable asset.
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Contact Info

Connect with our experts to see how MadeAi slashes literature review time and costs.

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